Tissue engineered skin offers promise as an alternate wound healing treatment when sufficient amounts of autograft are not available, such as in massive burns. Tissue engineered skin is typically much weaker than normal human skin. As a result, it is difficult to apply surgically and is easily subject to damage by mechanical shear. The goal of research performed at The Ohio State University using a TestResources 100R tissue test machine was to investigate the evolution of mechanical properties in engineered skin tissue. Results aimed to correlate changes in mechanical strength and stiffness with biological activity, including differentiation and proliferation. From this data, mathematical relations were developed to describe the time dependant-behavior of engineered skin tissues. These relations could be utilized to set load and strain limitations for dynamic mechanical stimulation of engineered skin. Learn more: Study of epidermal differentiation governing engineered skin biomechanics at Ohio State
Recommended Test Machine
Forces up to 10 kN (2,250 lbf)
Low force tabletop systems
Modular series of five frame options with adjustable test space
Affordable testing option for tension, compression, bend, peel and much more
Recommended Testing Accessories
Allows for testing in temperature-controlled water or saline solution
PID controlled temperature up to 45°C (113°F)
Size is optimized per application
Accompanied by a broad set of accessories that are designed for biomedical baths